GUANIDINE COMPOUNDS. II. PREPARATION OF MONO- AND N,N-DI-ALKYLGUANIDINES
- 1 November 1958
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 36 (11) , 1541-1549
- https://doi.org/10.1139/v58-225
Abstract
1-Guanyl-3,5-dimethylpyrazole nitrate is superior to S-methylisothiouronium sulphate as a reagent for preparation of simple salts of mono- and N,N-di-alkylguanidines from cyclohexylamine, trans-2-aminocyclohexanol, pyrrolidine, and piperidine. S-Methylisothiouronium sulphate, however, gave a higher conversion in the case of dimethylamine. Cyanamide is not as useful a guanylating agent as those mentioned above. The paper chromatography of the mono- and N,N-di-alkylguanidines and the parent amines was studied using four solvent systems.Keywords
This publication has 5 references indexed in Scilit:
- The Sakaguchi and Biacetyl Reactions for the Identification of Alkyl GuanidinesJournal of the American Chemical Society, 1953
- Studies in the Pyrazole Series. III. Substituted Guanidines1,2Journal of the American Chemical Society, 1953
- The Preparation of Some Structurally Related MonoguanidinesJournal of the American Chemical Society, 1933
- THE PREPARATION OF ALKYLGUANIDINESJournal of the American Chemical Society, 1923
- Ueber Derivate und Constitution des SchwefelharnstoffsEuropean Journal of Inorganic Chemistry, 1881