Relationship of Preexisting Dengue Virus (DV) Neutralizing Antibody Levels to Viremia and Severity of Disease in a Prospective Cohort Study of DV Infection in Thailand
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- 15 March 2004
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 189 (6) , 990-1000
- https://doi.org/10.1086/382280
Abstract
Background. Infection with any 1 of the 4 dengue viruses (DVs) can produce several illnesses, ranging from a mild febrile illness to classic dengue fever (DF) to dengue hemorrhagic fever (DHF), a potentially life-threatening disease. Most DHF cases occur after sequential heterotypic DV infections. The role of preexisting humoral immunity in modifying severity of dengue disease is not well understood.Keywords
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