Identification of Amino Acid Residues within the N-Terminal Domain of EspA That Play a Role in EspA Filament Biogenesis and Function
- 15 March 2008
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 190 (6) , 2221-2226
- https://doi.org/10.1128/jb.01753-07
Abstract
Enteropathogenic Escherichia coli employs a filamentous type III secretion system, made by homopolymerization of the translocator protein EspA. In this study, we have shown that the N-terminal region of EspA has a role in EspA's protein stability, interaction with the CesAB chaperone, and filament biogenesis and function.Keywords
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