The Effects of Adrenergic Blocking Agents on Passive Cutaneous Anaphylaxis Reactions in the Rat

Abstract
The effects of adrenergic blocking agents on inflammation have been investigated in rats utilising passive cutaneous anaphylaxis induced with anti-BSA antibodies (rat IgGa or rabbit IgG) and BSA. It was concluded that blocking agents do not affect the pathways leading to the release of phlogistic mediators. Our findings have confirmed the role of catecholamines as factors controlling the inflammatory response and have suggested, furthermore, that hormonal activity is mediated by β-adrenergic receptors.

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