THE EFFECT OF SODIUM BENTONITE ADMINISTRATION ON VITAMIN A METABOLISM IN THE RAT

Publisher Website
Google Scholar
Abstract
The inclusion of sodium bentonite in the diet severely limited the ability of vitamin A deficient rats to store the vitamin in the liver. This effect was observed both with vitamin A and with the provitamin β-carotene. Moreover, the liver weight per 100 gm. body weight was found to be less in most of the groups receiving sodium bentonite than in control groups. The results may be interpreted in terms of a physical adsorption of vitamin A or β-carotene on sodium bentonite present in the small intestine. Sodium bentonite cannot be regarded as an inert ingredient of the diet of rats and its prolonged administration might be expected to have deleterious effects.

This publication has 0 references indexed in Scilit: