The demonstration of latent particulate aminopeptidase activity

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Abstract
SYNOPSIS: The histochemical demonstration of aminopeptidase activity has been studied in unfixed frozen sections; it has been shown that Fast Blue B permits less diffusion than do two other coupling agents. With this tetrazonium salt the enzyme has been localized predominantly in discrete particles in the liver, intestine, and kidney of the rat. Evidence is offered indicating that these particles may be true cellular organelles, the properties of which may be akin to those of the lysosomes.