Rate of Metabolism of 9,10-Dimethyl-1,2-Benzanthracene in Newborn and Adult Mice.
- 1 May 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 113 (1) , 110-112
- https://doi.org/10.3181/00379727-113-28292
Abstract
Summary Determination of the proportion of free 9,10-dimethyl-1,2-benzanthracene remaining in newborn and in adult mice following intraperitoneal injection, revealed that this compound disappeared more quickly from the adult than from the newborn animals. This supports the view that the greater susceptibility of the newborn to tumor induction by this carcinogen is due to longer persistence of the compound in the newborn than in the adult.Keywords
This publication has 3 references indexed in Scilit:
- Tumours of Many Sites Induced by Injection of Chemical Carcinogens into Newborn Mice, A Sensitive Test for Carcinogenesis: The Implications for Certain Immunological TheoriesBritish Journal of Cancer, 1961
- Induction of Tumors in Newborn Mice With Dibenz[a,h]anthracene and 3-MethylcholanthreneJNCI Journal of the National Cancer Institute, 1961
- The effects of carcinogenic chemicals in newborn miceCancer, 1961