Ulcerative Colitis/Colon Cancer: Immunologically Linked Disorders?
- 6 July 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 287 (1) , 43
- https://doi.org/10.1056/nejm197207062870112
Abstract
Students of inflammatory bowel disease have long appreciated that immunologic factors participate somehow in its pathogenesis. Broberger and Perlmann1 and Kraft and Kirsner2 gave early attention to this matter but did not resolve whether immunologic mechanisms were pathogenetic or represented secondary phenomena.The paper by Rule et al. in this issue of the Journal presents newer findings resulting from studies of carcinoembryonic antigen (CEA). They report approximately 30 per cent CEA positivity both in ulcerative colitis and in Crohn's disease, supporting findings previously reported in the Journal with use of the same plasma method.3 Using Gold's serum technic and reagents, . . .Keywords
This publication has 3 references indexed in Scilit:
- Immunologic Diagnosis and Prognosis of Human Digestive-Tract Cancer: Carcinoembryonic AntigensNew England Journal of Medicine, 1972
- Demonstration of an Antigen Common to Several Varieties of NeoplasiaNew England Journal of Medicine, 1971
- AUTOANTIBODIES IN HUMAN ULCERATIVE COLITISThe Journal of Experimental Medicine, 1959