Synthesis, Transport, and Release of Posterior Pituitary Hormones
- 25 January 1980
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 207 (4429) , 373-378
- https://doi.org/10.1126/science.6153132
Abstract
Vasopressin and oxytocin are made and released by neurons of the hypothalamo-neurohypophysial system. Pulse labeling these neurons with radioactive amino acid indicates that the two hormones and their respective neurophysin carrier proteins are synthesized as parts of separate precursor proteins. The precursors seem to be processed into smaller, biologically active molecules while they are being transported along the axon.This publication has 28 references indexed in Scilit:
- Immunological and biochemical characterization of distinct high molecular weight forms of neurophysin and somatostatin in mouse hypothalamus extractsFEBS Letters, 1979
- ELECTROPHORETIC ANALYSES OF PROTEINS TRANSPORTED TO THE RAT POSTERIOR PITUITARYJournal of Neurochemistry, 1978
- CALCIUM AND NEUROSECRETION*Annals of the New York Academy of Sciences, 1978
- Immunological identification of rat neurophysin precursorsNature, 1977
- Biosynthesis and axonal transport of rat neurohypophysial proteins and peptides.The Journal of cell biology, 1977
- Ultrastructural studies on the localization of neurohypophysial hormones and their carrier proteins.Journal of Histochemistry & Cytochemistry, 1976
- A REVIEW ON NEUROSECRETORY GRANULES: THEIR CONTENTS AND MECHANISMS OF RELEASEAnnals of the New York Academy of Sciences, 1975
- AXONAL TRANSPORT OF PROTEINS IN THE HYPOTHALAMO‐NEUROHYPOPHYSIAL SYSTEM OF THE RATJournal of Neurochemistry, 1971
- VASOPRESSIN BIOSYNTHESIS—I. IN VIVO STUDIES*Journal of Neurochemistry, 1960
- A MAJOR COMPONENT OF NEUROHYPOPHYSIAL TISSUE ASSOCIATED WITH ANTIDIURETIC ACTIVITYJournal of Neurochemistry, 1959