INFLUENCE OF REPRODUCTIVE STAGE UPON THE FERTILITY OF GONADOTROPHINTREATED FEMALE RABBITS

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Abstract
Gonadotrophic preparations have been used experimentally to bring about the ovulation of fertilizable ova in mice (Engle, 1927) rats (Cole, 1937; Evans and Simpson, 1940) and rabbits (Pincus, 1940). No adequate estimates have been made, however, of the initial fertility of the eggs in these species. In some larger animals, there is the suggestion that the fertility of the eggs is affected by the stage of the reproductive cycle at the time of treatment. Cows treated in the early part of the estrous cycle yielded no fertilized eggs (Zavadovskii et al. 1935; Casida et al. 1940; Casida et al. 1943). but good fertility was obtained by the latter workers in those treated late in the cycle. Fertility has also been obtained in sheep treated in the follicular phase of the estrous cycle (Loginova and Lopyrin, 1938; Parkes and Hammond, 1940; Hammond et al. 1942).

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