Observations on the Stereochemical Outcome of the UGI Four-Component Condensation
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (1) , 1-12
- https://doi.org/10.1080/00397918908050946
Abstract
Investigations were carried out to explain the unexpected distribution of cis and trans products from the Ugi four-component condensation involving a cyclic imine. The nature of the transition state complex was deemed to be a determining factor. The influence of solvent polarity on the isomeric ratio of the products was also examined.Keywords
This publication has 3 references indexed in Scilit:
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- Peptide SynthesesPublished by Elsevier ,1971
- Four-Component Condensations and Related ReactionsPublished by Elsevier ,1971