Modulation of Vascular Smooth Muscle Signaling by Reactive Oxygen Species
Open Access
- 1 August 2006
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 21 (4) , 269-280
- https://doi.org/10.1152/physiol.00004.2006
Abstract
Modulation of signaling in vascular cells by reactive oxygen species (ROS) affects many aspects of cellular function, including growth, migration, and contraction. NADPH oxidases, important sources of ROS, regulate many growth-specific and migration-related signaling pathways. Identifying the precise intracellular targets of ROS enhances understanding of their role in cardiovascular physiology and pathophysiology.Keywords
This publication has 128 references indexed in Scilit:
- Reactive oxygen species and ERK 1/2 mediate monocyte chemotactic protein-1-stimulated smooth muscle cell migrationJournal of Biomedical Science, 2005
- Pyk2- and Src-Dependent Tyrosine Phosphorylation of PDK1 Regulates Focal AdhesionsMolecular and Cellular Biology, 2003
- NAD(P)H Oxidase-Derived Reactive Oxygen Species as Mediators of Angiotensin II SignalingAntioxidants and Redox Signaling, 2002
- Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylationBiochemical and Biophysical Research Communications, 2002
- Reactive Oxygen and NF-κB in VEGF-Induced Migration of Human Vascular Smooth Muscle CellsBiochemical and Biophysical Research Communications, 2001
- Src family kinases are required for integrin but not PDGFR signal transductionThe EMBO Journal, 1999
- Modulation of glutathione peroxidase activity in human vascular endothelial cells by fatty acids and the cytokine interleukin-1 βBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996
- Assembly of the Human Neutrophil NADPH Oxidase Involves Binding of p67 and Flavocytochrome to a Common Functional Domain in p47Published by Elsevier ,1996
- Dynamics of beta 1 integrin-mediated adhesive contacts in motile fibroblasts.The Journal of cell biology, 1992
- Regulation of manganese superoxide dismutase: IL-1 and TNF induction in pulmonary artery and microvascular endothelial cellsBiochemical and Biophysical Research Communications, 1992