Stress and the Aching Heart

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Abstract
Every affection of the mind that is attended with either pain or pleasure, hope or fear, is the cause of an agitation whose influence extends to the heart.William Harvey, 16281 Written more than 350 years ago, Harvey's allusion to an intimate association between neural factors and the heart received some attention in anecdote and fable, yet it was not subjected to systematic direct scientific inquiry until the 1960s. Over the past 20 years we have greatly refined our approach to identifying persons at risk for cardiac death.When it was found that in most cases persons experiencing sudden cardiac . . .