The structure of vacidin A, an aromatic heptaene macrolide antibiotic. I. Complete assignment of the 1H NMR spectrum and geometry of the polyene chromophore.
- 1 January 1989
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 42 (11) , 1631-1638
- https://doi.org/10.7164/antibiotics.42.1631
Abstract
The constitution of vacidin A, a representative of the aromatic heptaene macrolide antibiotics was established on the basis of 13C and 1H-1H double quantum filtered correlated spectroscopy, rotating frame nuclear Overhauser effect spectroscopy, J-resolved 1H as well as 1H-13C correlation NMR spectra. Geometry of the polyene chromophore was determined as 22E,24E,26E,28Z, 30Z,32E,34E.This publication has 0 references indexed in Scilit: