A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias
Open Access
- 7 March 2002
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 116 (4) , 758-764
- https://doi.org/10.1046/j.0007-1048.2002.03340.x
Abstract
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.Keywords
This publication has 27 references indexed in Scilit:
- Cryptic t(4;11) encoding MLL-AF4 due to insertion of 5′ MLL sequences in chromosome 4Leukemia, 2001
- The detection and significance of chromosomal abnormalities in childhood acute lymphoblastic leukaemiaBlood Reviews, 2001
- Sensitivity of FISH in detection ofMLL translocationsGenes, Chromosomes and Cancer, 2000
- A DNA probe combination for improved detection ofMLL/11q23 breakpoints by double-color interphase-FISH in acute leukemiasGenes, Chromosomes and Cancer, 2000
- Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe setLeukemia, 1999
- MLL rearrangements in haematological malignancies: lessons from clinical and biological studiesBritish Journal of Haematology, 1999
- Leukemia in InfantsThe Oncologist, 1999
- Cytogenetic studies of infant acute lymphoblastic leukemia: poor prognosis of infants with t(4;11) – a report of the Children’s Cancer GroupLeukemia, 1999
- The der(11)-encoded MLL/AF-4 fusion transcript is consistently detected in t(4;11)(q21;q23)-containing acute lymphoblastic leukemiaBlood, 1994
- The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 geneCell, 1992