The Quantitative Variation of Serum Proteins. Electrophoretic Studies of Twin Materials

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Abstract
Total serum protein and electrophoretic serum protein fractions have been determined for two primary materials of twins, comprising 383 and 268 sera, respectively. The twins had not been examined clinically but were on the whole subjectively healthy. After certain exclusions, data from 330 and 234 sera, respectively, remained for statistical analysis. A trend toward closer agreement between monozygotic twins as compared to dizygotic twins was found, and both types of twins showed closer agreement that the statistical equivalents of unrelated people. This was true for total serum protein as well as for all protein fractions. It was concluded that the concentrations of the various serum proteins are evidently controlled by both genetical and environmental factors, the relative importance of which is, however, impossible to judge.

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