Intravenous Gammaglobulin, Thrombocytopenia, and the Acquired Immunodeficiency Syndrome
- 1 September 1985
- journal article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 103 (3) , 478-479
- https://doi.org/10.7326/0003-4819-103-3-478_2
Abstract
To the editor: Recently, Mintzer and coworkers (1) reported the cases of three patients with immune thrombocytopenia, Kaposi's sarcoma, and the acquired immunodeficiency syndrome. Two of these patients were treated with high-dose intravenous gammaglobulin without benefit. We report the cases of two patients with thrombocytopenia associated with the syndrome who had a dramatic increase in platelet counts after such treatment. Patient 1: A 29-year-old white homosexual man had had thrombocytopenia (platelet count, < 30 X 109/L) for more than a year. His platelet-associated IgG level was significantly elevated, the lymphocyte T4/T8 ratio was low (0.40), and a serologic test forThis publication has 4 references indexed in Scilit:
- Suppressor cell function after intravenous gammaglobulin treatment in adult chronic idiopathic thrombocytopenic purpuraBritish Journal of Haematology, 1985
- Treatment of Kaposi's Sarcoma and Thrombocytopenia with Vincristine in Patients with the Acquired Immunodeficiency SyndromeAnnals of Internal Medicine, 1985
- On the Mechanism of Thrombocytopenic Purpura in Sexually Active Homosexual MenNew England Journal of Medicine, 1984
- Hemophilia and thrombocytopenia in a patient with impaired cellular immunityAnnals of Hematology, 1984