Salmonella meningitis in infancy

Abstract
Despite adequate treatment, mortality and morbidity were high among the 13 cases of Salmonella meningitis in this series. Chloramphenicol, being a bacteriostatic agent against Salmonella spp., is not a suitable antibiotic for the treatment of Salmonella meningitis. Treatment for 4-6 wk is recommended with use of an antibiotic capable of achieving an adequate bactericidal concentration in the CSF such as moxalactam. Intraventricular antibiotic treatment should be considered if there is a delay in the eradication of the Salmonella organisms from the CSF after starting treatment.

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