Mitoses in the Livers of Rats Treated with Thiourea

Abstract
Thirty-six d" albino rats (70-100 gs. in wt.) were injected intraperit. at daily intervals with 4 ml. of a 10% aq. soln. of thiourea. Rats which died or were sacrificed during the first 24-31 hrs. showed no mitoses in the liver cells. Liver tissue from rats which had received 3 injns. showed 12-18 mitoses in each microscopic field. Both normal and pathologic mitoses were observed.

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