Mitochondria, Calcium Regulation, and Acute Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells

1 December 1996

journal article
research article
Published by Wiley in Journal of Neurochemistry

Vol. 67 (6) , 2282-2291
https://doi.org/10.1046/j.1471-4159.1996.67062282.x

Abstract

Exposure of cultured cerebellar granule cells to 100 µM glutamate plus glycine in the absence of Mg2+ causes calcium loading of the in situ mitochondria and is excitotoxic, as demonstrated ...

Keywords

CALCIUM
GLUTAMATE
EXCITOTOXICITY
GRANULE CELL
MITOCHONDRIA
ATP
MITOCHONDRIAL MEMBRANE POTENTIAL

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