Possible Anti-tumor Promoting Properties of Edible Plants from Thailand, and Identification of an Active Constituent, Cardamonin, ofBoesenbergia pandurata

1 January 1993

journal article
Published by Taylor & Francis in Bioscience, Biotechnology, and Biochemistry

Vol. 57 (11) , 1971-1973
https://doi.org/10.1271/bbb.57.1971

Abstract

Possible anti-tumor promoting properties of a total of 40 methanol extracts from Thai edible plants, including 5 non-edible species, were estimated in vitro by an inhibition test of tumor promoter-induced Epstein-Barr virus (EBV) activation. Fourteen species (35% of the total) were found to be strongly active. In addition, cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) was identified as a potently active constituent (IC₅₀ = 3.1μM) of Boesenbergia pandurata (Zingiberaceae), suggesting it to be an effective anti-tumor promoter.

Keywords

ACTIVE CONSTITUENT
VIRUS
PROMOTING PROPERTIES
EDIBLE PLANTS
ANTI TUMOR
TUMOR PROMOTER
PANDURATA
BOESENBERGIA

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