Health implications of 2,3,7,8‐tetrachloro‐dibenzodioxin (TCDD) contamination of residential soil
- 1 January 1984
- journal article
- review article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 14 (1) , 47-93
- https://doi.org/10.1080/15287398409530562
Abstract
Extrapolations from animal toxicity experiments (including carcinogenicity and reproductive effects) to possible human heath effects can be used to estimate a reasonable level of risk for 2,3,7,8-tetrachlorodibenzodioxin (2,3,7,8-TCDD). Extrapolations are derived from: (1) review of published studies, (2) a complex set of assumptions related to human exposure to contaminated soil, and (3) estimates of (a) a dose response curve, (b) appropriate margins of safety, and/or (c) applicable mechanisms of action. One ppb of 2,3,7,8-TCDD in soil is a reasonable level at which to begin consideration of action to limit human exposure for contaminated soil.Keywords
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