A Unified Procedure for Diastereo- and Enantiocontrolled Construction of Compactin Lactone and Calcitriol Enyne
- 1 September 1997
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1997 (9) , 1111-1113
- https://doi.org/10.1055/s-1997-1550
Abstract
A unified diastereo- and enantiocontrolled entry into compactin lactone, an essential structural moiety for the biological activity of compactin, and calcitriol enyne, an A-ring precursor of calcitriol, has been developed by use of the same stereocontrol procedure starting from enantiomeric epichlorohydrins.Keywords
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