Down's Syndrome and the Dementia of Alzheimer Disease
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in International Review of Psychiatry
- Vol. 2 (1) , 43-52
- https://doi.org/10.3109/09540269009028270
Abstract
The clinical course and expression of dementia in persons with Down's Syndrome (DS) are poorly understood. While longitudinal studies are rare they provide the most accurate data since standardized psychological tests yield performances which show pronounced ‘floor effects’, except with mildly to moderately retarded persons. A review of the main psychological observations is provided along with reference to some of the major problems involved in assessment. A discussion is provided of the relationships between dementia and the Alzheimer disease (AD) process in DS.Keywords
This publication has 23 references indexed in Scilit:
- Age and pattern of intellectual decline among Down Syndrome and other mentally retarded adultsInternational Journal of Rehabilitation Research, 1988
- Serum amysoid A protein, albumin and prealbumin in Alzheimer's disease and in demented patients with Down's syndromeActa Neurologica Scandinavica, 1986
- Dementia of the Alzheimer TypeJournal of the American Geriatrics Society, 1986
- Ageing in Down's SyndromeThe British Journal of Psychiatry, 1985
- Facial Recognition Memory Deficits in Normal Aging and Senile DementiaJournal of Gerontology, 1980
- Clinical Value of the London Psychogeriatric Rating ScaleJournal of the American Geriatrics Society, 1978
- “Mini-mental state”Journal of Psychiatric Research, 1975
- Alzheimer Degeneration in Down SyndromeArchives of Neurology, 1975
- Alzheimer's Disease in Down's Syndrome: Visual Retention DeficitsCortex, 1974
- The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly SubjectsThe British Journal of Psychiatry, 1968