Microfilarial levels in cats infected with Brugia pahangi by two alternative routes

Abstract
The use of artificially produced puncture wounds as a route whereby Brugia pahangi larvae could be administered to a vertebrate host was tested in mice. Approximately 50% of the larvae administered were recovered in the tissues. This method of infection was then compared with that commonly used in experimental infections, namely inoculation with a syringe and needle. The differences in infections produced by these two procedures are too small and the number of observations too few to make any generalizations on the relative effectiveness of the two methods, but it is evident that patent infections can be produced in a natural host by using artificial puncture wounds, and this method of infection, perhaps with certain modifications, will probably be of value in subsequent studies on development and distribution of filarial nematodes in the vertebrate host.