EFFECT OF PIMOZIDE ON LEVODOPA‐INDUCED GROWTH HORMONE RELEASE IN MAN

Abstract
Serum growth hormone (GH) behavior after L-dopa administration was measured in 12 healthy subjects both in basal conditions and after a 4 day course of pimozide (4 mg daily), a specific blocker of dopamine (DA) receptors. In addition, fasting plasma GH was measured on the 1st, 2nd and 3rd day of treatment. No significant difference was found between GH response to L-dopa in basal conditions and after pimozide; moreover, fasting GH was uninfluenced by pimozide.