Complex formation of human alpha‐1–antitrypsin with components in Schistosoma mansoni cercariae

Abstract
SUMMARY: Human alpha‐1–antitrypsin (α1‐AT) was incubated with an extract of Schistosoma mansoni cercariae or porcine pancreatic elastase and analysed by immunoelectrophoresis and Western blotting. The inhibitor was shown to form complexes with components in S. mansoni cercariae in the same way as elastase. The role of α1‐AT in S. mansoni infection is discussed.