Long-Distance Charge Transport in DNA: The Hopping Mechanism
Top Cited Papers
- 20 June 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Accounts of Chemical Research
- Vol. 33 (9) , 631-636
- https://doi.org/10.1021/ar990040b
Abstract
Long-distance charge transport from a guanine radical cation (G+•) to a G-rich sequence is of biological importance. This reaction was studied by selective charge injection into a G, monitoring the charge transport to a GGG sequence by competing H2O-trapping. The efficiency of the charge transport diminished dramatically with increasing number of A:T base pairs between G+• and GGG. But in DNA strands where G's are located between the G+• and GGG sequence, long-distance charge transport occurred by a multistep hopping mechanism.Keywords
This publication has 19 references indexed in Scilit:
- DNA Responds to Ionizing Radiation as an Insulator, Not as a “Molecular Wire”Angewandte Chemie International Edition in English, 1999
- Electron Transfer Between Bases in Double Helical DNAScience, 1999
- Paradigms, supermolecules, electron transfer and chemistry at a distance. What's the problem? The science or the paradigm?JBIC Journal of Biological Inorganic Chemistry, 1998
- Distance Dependence of Photoinduced Electron Transfer in DNAAngewandte Chemie International Edition in English, 1998
- Evidence for Interacting Gas Flows and an Extended Volatile Source Distribution in the Coma of Comet C/1996 B2 (Hyakutake)Science, 1997
- How Easily Oxidizable Is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous SolutionJournal of the American Chemical Society, 1997
- Adjacent guanines as preferred sites for strand breaks in plasmid DNA irradiated with 193 nm and 248 nm UV laser lightJournal of Photochemistry and Photobiology B: Biology, 1996
- Electron Transfer through DNA: Site‐Specific Modification of Duplex DNA with Ruthenium Donors and AcceptorsAngewandte Chemie International Edition in English, 1995
- Long-Range Photoinduced Electron Transfer Through a DNA HelixScience, 1993
- Induction of Strand Breaks in Polyribonucleotides and DNA by the Sulphate Radical Anion: Role of Electron Loss Centres as Precursors of Strand BreakageInternational Journal of Radiation Biology, 1993