17 BETA-OL ANDROGENS AND FREE INDEX IN HIRSUTE AND HIRSUTE OBESE WOMEN

  • 1 January 1976
    • journal article
    • research article
    • Vol. 27  (8) , 916-920
Abstract
The mean levels of combined serum testosterone and dihydrotestosterone (T + DHT) and the free index (FI) were significantly higher and the mean dihydrotestosterone precipitation index (DHT-PI) signficantly lower in hirsute women than in normal women. Although the mean T + DHT values of the different groups of hirsute patients were comparable, the FI value of the oligomenorrheic and/or obese patient was higher than that of the nonobese, normally menstruating group. The mean DHT-PI level of obese patients was significantly lower than that of nonobese patients. The lowest androgen binding was in obese patients with oligomenorrhea. Hirsutism is associated with T + DHT values of 150 ng/dl or lower. Measurement of androgen binding and androgen levels in unchromatographed serum extracts provides valuable information in the treatment of hirsute women.

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