ACRODERMATITIS ENTEROPATHICA

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Abstract
A 6-mo.-old Saudi boy with acrodermatitis enteropathica confirmed by low serum Zn and alkaline phosphatase levels is described. Both the patient and a sibling developed acrodermatitis enteropathica while breastfed. The mother had low serum Zn levels. Cranial computed tomography initially showed marked central and cortical atrophy that improved on treatment with zinc sulfate. The importance of Zn for normal brain growth and function is well known and the improvement on cranial computed tomography could be explained by improved myelination.