Piroxicam, aspirin, and gastrointestinal blood loss
- 1 August 1982
- journal article
- research article
- Published by Wiley in Clinical Pharmacology & Therapeutics
- Vol. 32 (2) , 247-252
- https://doi.org/10.1038/clpt.1982.155
Abstract
A study to compare the effects of 3 piroxicam regimens and aspirin on fecal blood loss (FBL) was conducted among 39 healthy men. Of the subjects, 14 also underwent pre- and poststudy gastroscopy. There was an increase in FBL after aspirin 972 mg 4 times/day, whereas piroxicam 20 mg/day, 5 mg 4 times/day, and 10 mg 4 times/day induced no observable increase in fecal blood loss. There was gastroscopic evidence of irritation in the aspirin group, but not in any of the piroxicam groups.This publication has 2 references indexed in Scilit:
- Gastro-Intestinal Blood Loss during Administration of Indoprofen, Aspirin and IbuprofenJournal of International Medical Research, 1977
- Gastrointestinal blood loss. Effect of aspirin, fenoprofen, and acetaminophen in rheumatoid arthritis as determined by sequential gastroscopy and radioactive fecal markersJAMA, 1977