The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing

Open Access

6 October 2000

journal article
fj express-summary
Published by Wiley in The FASEB Journal

Vol. 14 (15) , 2373-2376
https://doi.org/10.1096/fj.00-0490fje

Abstract

Endostatin is a cleavage product of collagen XVIII that strongly inhibits tumor angiogenesis. To determine if endostatin affects other angiogenic processes, we generated full-thickness excisional wou...

Keywords

Funding Information

European Commission (BI04-CT96-0537)

This publication has 37 references indexed in Scilit:

Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1
Science, 1999
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
Oncogene, 1999
Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice
Science, 1999
Cell Type-Specific Expression of Angiopoietin-1 and Angiopoietin-2 Suggests a Role in Glioblastoma Angiogenesis
The American Journal of Pathology, 1998
Antiangiogenic tumour therapy: will it work?
Trends in Pharmacological Sciences, 1998
Crystal structure of the angiogenesis inhibitor endostatin at 1.5Aresolution
The EMBO Journal, 1998
Mechanisms of angiogenesis
Nature, 1997
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
Cell, 1996
DIFFERENTIAL REGULATION OF PRO-INFLAMMATORY CYTOKINES DURING WOUND HEALING IN NORMAL AND GLUCOCORTICOID-TREATED MICE
Cytokine, 1996
Cellular distribution of the mRNA for the κ-opioid receptor in the human neocortex: a non-isotopic in situ hybridization study
Neuroscience Letters, 1995