Corneal topography changes after a 15 second pause in blinking

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Abstract
To examine the effect of a short pause in blinking on the quantitative topographic parameters of the corneal surface. Refractive corneal surgery unit of a university eye hospital. Using a TMS-1 instrument (Computed Anatomy, Inc.), corneal topographic parameters were measured 5 and 15 seconds after a complete blink in 12 healthy subjects. The main outcome measures were changes in the surface regularity index (SRI) and the surface asymmetry index (SAI). During the pause in blinking, the mean SRI value increased from 0.18 ± 0.19 (SD) to 0.30 ± 0.19 (P < .02) and the SAI from 0.21 ± 0.08 to 0.24 ± 0.10 (P = .079, not statistically significant). There were no significant changes in the values for potential visual acuity, corneal refractive power, or astigmatism. The results indicated a significant change in corneal topography during even a short pause in blinking. In follow-up studies using corneal topography, all measurements should be done at a fixed time after a complete blink.

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