Polymorphonuclear Leukocytes May Impair Endothelial Function
Open Access
- 1 June 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 25 (6) , 1262-1267
- https://doi.org/10.1161/01.atv.0000163842.91226.ba
Abstract
Objectives— To examine whether polymorphonuclear leukocytes (PMNs) in hypercholesterolemia (HC) are activated to generate large amount of superoxide in vivo and hence impair endothelial function and, if so, whether statins, which possess anti-inflammatory properties, may restore PMN-mediated endothelial dysfunction.Keywords
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