Syntheses of Novel Chitosan Derivatives Soluble in Organic Solvents by Regioselective Chemical Modifications
- 1 February 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 19 (2) , 243-246
- https://doi.org/10.1246/cl.1990.243
Abstract
Regioselective chemical modifications of chitosan were successfully carried out in homogeneous solution under mild condition using phthalimido chitosan as a key starting material. Discrimination between the primary and secondary hydroxyl groups were also examined by O-tritylation or O-tosylation. As anticipated, the new chitosan derivatives exhibited a much improved solubility in common organic solvents.Keywords
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