NUCLEOLAR ORGANIZING REGIONS OF NORMAL CHINESE-HAMSTER AND CHW CELL-LINE CHROMOSOMES

  • 1 January 1979
    • journal article
    • research article
    • Vol. 25  (97) , 37-43
Abstract
Chromosome preparations from fibroblasts or normal male and female Chinese hamsters and the cell line CHW were stained with AgNO3. Ag stain was usually localized at the telomeres of autosomes. The marker chromosome M1 in the CHW cell line has Ag-NOR [nucleolus organizer region] near the center of the long arm, which indicates that either the long arms of chromosome 5 fused at the telomeres or the intact telomeric region of 1 chromosome fused, with 1 a deleted telomere. The variation of Ag-NOR number per cell and Ag-heteromorphism in chromosome 4 were observed. The Ag-NOR of chromosomes 4 and 5 are in approximately the same position as the positive C[constitutive heterochromatin]-bands, and these may play a role in the preservation of heterochromatin.

This publication has 0 references indexed in Scilit: