Loss of Rb-E2F Repression Results in Caspase-8-mediated Apoptosis through Inactivation of Focal Adhesion Kinase
Open Access
- 1 March 2005
- journal article
- Published by Elsevier
- Vol. 280 (11) , 10484-10490
- https://doi.org/10.1074/jbc.m409371200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Differential regulation of apoptotic genes by Rb in human versus mouse cellsOncogene, 2004
- Direct coupling of the cell cycle and cell death machinery by E2FNature Cell Biology, 2002
- Mouse models of cell deathNature Genetics, 2001
- The Rb/E2F pathway: expanding roles and emerging paradigmsGenes & Development, 2000
- Rb function in cell-cycle regulation and apoptosisNature Cell Biology, 2000
- The Hallmarks of CancerCell, 2000
- Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.Proceedings of the National Academy of Sciences, 1995
- Mechanism of active transcriptional repression by the retinoblastoma proteinNature, 1995
- Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.Proceedings of the National Academy of Sciences, 1994
- Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.Molecular and Cellular Biology, 1993