THE FACILE SYNTHESIS OF MACROCYCLIC LACTONES BY THE USE OF 2-CHLORO-3-METHOXYMETHYL-1-METHYLPYRIDINIUM IODIDE
- 5 July 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 6 (7) , 763-766
- https://doi.org/10.1246/cl.1977.763
Abstract
Long chain ω-hydroxycarboxylic acids cyclize to the corresponding lactones in good yields by the treatment with 2-chloro-3-methoxymethyl-1-methylpyridinium iodide (2) and triethylamine in refluxing methylene chloride.Keywords
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