Relationship Between Ketosteroid Excretion and Basal Oxygen Consumption in Children

Abstract
Basal O2 consumption, leg muscle size,and 2 measures of urinary ketosteroids were investigated in 20 boys and 28 girls. Though comparable in the range of excreted ketosteroids, muscle mass and reasonably com-parable in basal O2 consumption, ketosteroid_02 correlations were 0.77 [plus or minus] .09 in the boys and 0.37 [plus or minus] .17 in the girls. Corrected for differences in muscle mass, ketosteroid O2 correlations continued to exceed 0.6 in the boys, and dropped to or below 0.11 in the girls with both the 17 ketosteroids (Zimmerman reagent) and the total ketosteroids (DNPH reagent). It was evident that in the urine of the boys there were nonvolatile carbonyl compounds, presumably ketonic steroids, moderately correlated with basal O2 consumption but in the urine of the girls, such compounds appeared to be absent. It was suggested that the higher basal requirements of the male, per unit of muscle mass, are attributable to qualitative rather than quantitative differences in the level of hormones produced.

This publication has 1 reference indexed in Scilit: