Subcutaneous fat necrosis of the newborn

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Abstract
Specimens from 2 cases of subcutaneous fat necrosis of the newborn were studied by light and EM. Crystallization of the fat cell started with clearing of the central fat droplet, followed by the appearance of cylindrical crystals. The fat crystals were phagocytosed by cytoplasmic projections of macrophages and by foreign body giant cells. Ca deposits were demonstrated within the central fat droplet of the degenerated fat cell of Case 2.