Retinoids and Carotenoids as Inhibitors of Carcinogenesis and Inducers of Cell-Cell Communication
- 27 April 2009
- journal article
- review article
- Published by Oxford University Press (OUP) in Nutrition Reviews
- Vol. 50 (9) , 270-274
- https://doi.org/10.1111/j.1753-4887.1992.tb01345.x
Abstract
In cell cultures of carcinogen-initiated fibroblasts, a number of retinoids and carotenoids can reversibly inhibit progression to the transformed state. The anticarcinogenic action of retinoids and carotenoids is closely correlated with enhanced gap-junction cell-to-cell communication and with increased synthesis of the gap-junction protein, connexin.Keywords
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