SEVERE SULFADIAZINE HYPERSENSITIVITY IN A CHILD WITH REACTIVATED CONGENITAL TOXOPLASMIC CHORIORETINITIS
- 1 March 2006
- journal article
- case report
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 25 (3) , 270-272
- https://doi.org/10.1097/01.inf.0000202070.59190.9a
Abstract
A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines. Symptoms resolved when systemic corticosteroids were administered. This case underscores problems in clinical management with sulfadiazine hypersensitivity, potential immunosuppression from corticosteroids and selection of medications for recurrences of toxoplasmic chorioretinitis.Keywords
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