Normal IncA Expression and Fusogenicity of Inclusions in Chlamydia trachomatis Isolates with the incA I47T Mutation
Open Access
- 1 July 2001
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 69 (7) , 4654-4656
- https://doi.org/10.1128/iai.69.7.4654-4656.2001
Abstract
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype.Keywords
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