A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100
- 1 November 1991
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 35 (11) , 2436-2439
- https://doi.org/10.1128/aac.35.11.2436
Abstract
A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.Keywords
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