Fluorous Dienophiles Are Powerful Diene Scavengers in Diels−Alder Reactions
- 14 August 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (18) , 3293-3296
- https://doi.org/10.1021/ol035214a
Abstract
Three fluorous dienophiles have been synthesized, and their value in scavenging an excess diene after Diels−Alder reactions is shown. The resulting fluorous derivatives are separated by solid-phase extraction on fluorous silica gel (FSPE). The fluorous [1,2,4]triazoline-3,5-dione 10 reacted with most dienes within seconds or minutes.Keywords
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