Nucleotide sequence and characteristics of a Ty element from yeast
- 1 January 1985
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 13 (8) , 2745-2758
- https://doi.org/10.1093/nar/13.8.2745
Abstract
We have determined the nucleotide sequence of a complete yeast Ty element (Ty-pY109) which is located near a tRNA(Lys1) gene. The element is 5912 bp in length; the internal domain is flanked by two identical delta sequences of 331 bp. Ty-pY109 contains two large open reading frames (ORFs) which overlap by 38 bp; the putative proteins consist of 440 and 1328 amino acid residues, respectively. The organisation of the coding sequences in Ty resembles that found in retroviral proviruses and the copia-like elements in Drosophila. Partial homologies have been found between Ty-ORF1 and tnpA from Tn3, and Ty-ORF2 and a reverse transcriptase-like domain (1,2).Keywords
This publication has 40 references indexed in Scilit:
- Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa typeJournal of Molecular Biology, 1984
- Retrovirus-like particles containing RNA homologous to the transposable element copia in Drosophila melanogasterNature, 1983
- Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucineCell, 1982
- Delta sequences and double symmetry in a yeast chromosomal replicator regionJournal of Molecular Biology, 1982
- Sequence variation in dispersed repetitive sequences in Saccharomyces cerevisiaeJournal of Molecular Biology, 1981
- Transposable elements associated with constitutive expression of yeast alcohol dehydrogenase IICell, 1981
- Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genesCell, 1980
- The Origins of Gene Instability in YeastScience, 1980
- Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplicationNature, 1980
- Sequence of retrovirus provirus resembles that of bacterial transposable elementsNature, 1980