Relationship of In Vitro Binding of Digoxin to its Intestinal Absorption in Rats

1 November 1973

journal article
Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology

Vol. 51 (11) , 832-834
https://doi.org/10.1139/y73-127

Abstract

Digoxin is bound in aqueous solution to cholestyramine and various commercially available antacids. However, chronic ingestion of cholestyramine and an antacid in rats does not interfere with the intestinal absorption of digoxin.

Keywords

INGESTION
INTESTINAL ABSORPTION
AQUEOUS
ANTACID
INTERFERE
VITRO BINDING
BINDING OF DIGOXIN

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