Transepidermal Water Loss Dynamics of Human Vulvar and Thigh Skin
- 6 May 2005
- journal article
- clinical trial
- Published by S. Karger AG in Skin Pharmacology and Physiology
- Vol. 18 (3) , 139-143
- https://doi.org/10.1159/000084911
Abstract
Refinement in procedures to assess skin surface water loss (SSWL) dynamics of the vulvar skin on a large sample of subjects (60) is described and compared to another semi-occluded skin site, the inner thigh. Vulvar SSWL significantly decreased over a 30-min period from 46.2 +/- 2.6 (SE) to 24.7 +/- 1.6 g m(-2) h (p < 0.001). The inner thigh, another semi-occluded region, showed no similar pattern for SSWL (6.2 +/- 0.3 to 6.6 +/- 0.5 g m(-2) h), and the values were significantly less than those for vulvar skin. There was no significant effect of age, body mass index or atopic status on vulvar SSWL.Keywords
This publication has 11 references indexed in Scilit:
- Effects of Prolonged Occlusion on Stratum corneum Barrier Function and Water Holding Capacity1Skin Pharmacology and Physiology, 1999
- Time-Dependent Variations of the Skin Barrier Function in Humans: Transepidermal Water Loss, Stratum Corneum Hydration, Skin Surface pH, and Skin TemperatureJournal of Investigative Dermatology, 1998
- Barrier function parameters in various keratinization disorders: transepidermal water loss and vascular response to hexyl nicotinateBritish Journal of Dermatology, 1993
- Cutaneous responses to topical methyl nicotinate in human forearm and vulvar skinJournal of Dermatological Science, 1991
- Menstrual cycle and skin reactivityJournal of the American Academy of Dermatology, 1991
- Sodium lauryl suifate-induced irritant contact dermatitis in vulvar and forearm skin of premenopausal and postmenopausal womenJournal of the American Academy of Dermatology, 1990
- Guidelines for transepidermal water loss (TEWL) measurementContact Dermatitis, 1990
- Frictional Properties of Human Forearm and Vulvar Skin: Influence of Age and Correlation with Transepidermal Water Loss and CapacitanceDermatology, 1990
- Human cutaneous vulvar reactivity to irritantsContact Dermatitis, 1979
- Effect of Prolonged Occlusion on the Microbial Flora, pH, Carbon Dioxide and Transepidermal Water Loss on Human SkinJournal of Investigative Dermatology, 1978