Anaphylactic symptoms due to chlorhexidine gluconate
- 1 January 1989
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 125 (1) , 50-52
- https://doi.org/10.1001/archderm.125.1.50
Abstract
• Six patients who developed urticaria, dyspnea, and anaphylactic shock due to topical application of chlorhexidine gluconate solution are described. Chlorhexidine gluconate was confirmed as the causative agent of type I hypersensitivity by intradermal, scratch, and epicutaneous tests. To prevent life-threatening adverse reactions, it seems important to use chlorhexidine gluconate on wound surfaces at a concentration of 0.05%, as recommended by the manufacturer; chlorhexidine gluconate may not be suitable for application to mucous membranes. (Arch Dermatol1989;125:50-52)This publication has 0 references indexed in Scilit: