A Prospective, Randomized Trial to Assess the Cost Impact of Pharmacist-Initiated Interventions

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Abstract
ALTHOUGH MANY investigators have evaluated the impact of clinical interventions by pharmacists, the economic benefits have never been fully assessed in a prospective, randomized trial.1 Some have compared their interventions with a control group, but most of these studies were not randomized, limited their interventions to specific medications (such as antibiotics or H2-receptor antagonists), or used patient charges rather than actual costs when determining the economic impact of their services.2-16 We report the results of a large, prospective, randomized evaluation of pharmacist-initiated interventions at our institution using pharmacy acquisition costs to estimate true economic benefits.